RESEARCH NEWS
FROM HHMI

MicroRNAs Intimately Involved in Cancer
(06.09.05)
HHMI investigators have established that tiny RNAs provide a novel genetic route to the initiation of some forms of cancer.

Genetic Tool Reaps Rich Harvest
(04.08.05)
In one fell swoop, scientists have increased from dozens to hundreds the number of known genes that control crucial steps in the development of many organisms from fruit flies to humans.

New RNA Libraries Can Inactivate Human Genes Selectively
(03.25.04)
Researchers have generated large RNA libraries that can be used to turn off individual human and mouse genes to study their function.

Researchers Adapt RNAi to Study Gene Function on a Large Scale
(02.06.04)
HHMI researchers characterized the role in growth and viability of nearly all the genes in the genome of the fruit fly.

Paralyzed Worms Add Pieces to the Puzzle of RNA Interference
(09.15.00)
HHMI researchers pinpoint several genes involved in RNA interference.

HHMI SCIENTISTS AND RNAi

David Bartel

Brenda Bass

Stephen Elledge

H. Robert Horvitz

Scott Lowe

Craig Mello

Norbert Perrimon

FROM THE HHMI BULLETIN

A World Apart
A group of scientists with mammoth imaginations and the best biotech tools is piecing together a view of a prehistoric world where RNA ruled.

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HHMI Bulletin: May 2012

Cover Story: Cells on the Move
Exploring the building blocks of cell movement, researchers are revealing delightful dances—and changing dogma.

Enter the Samurai
Loren Looger likes to solve other people's problems—at least their technical ones. That's working out well for his Janelia Farm colleagues.

Making Bigger Better
Scaling up research opportunities in introductory science courses requires a new way of thinking and working.

Opening the Floodgates
To speed the hunt for disease-related genes, researchers are delving into the exome, the fraction of the genome responsible for encoding proteins.