RESEARCH NEWS
FROM HHMI

Mutant Mouse Mimics Human Bone Cancer
(06.16.08)
HHMI researchers have developed a mouse model of osteosarcoma, the most common form of bone cancer.

New Genetic Barcoding Technique Identifies Dozens of Targets for Cancer Drugs
(02.01.08)
HHMI investigators are beginning to examine every gene in the genome to figure out which genes are deleterious to tumor cells.

A Genetic "Gang of Four" Drives Spread of Breast Cancer
(04.12.07)
Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs.

Common Molecule Notifies Immune System of Prostate Cancer
(01.11.08)
In experiments with mice, researchers have found that the body’s immune system can use a surprisingly common molecule to recognize prostate tumors.

HHMI SCIENTISTS AND ANGIOGENESIS

D. Gary Gilliland

Todd R. Golub

Joan Massagué

Shahin Rafii

Boris O. Kopnin

FROM THE HHMI BULLETIN

Putting the Brakes on Cancer
(May 2007)
By reactivating p53—a renowned tumor-suppressor gene—researchers are stopping even advanced cancers in mice.

Bringing Down Cancer's House of Cards
(February 2008)
Defining an elaborate yet fragile control pathway offers a new strategy for toppling many cancers.

FROM BIOINTERACTIVE

Angiogenesis

The Evolution of Cancer

Understanding Cancer Diversity

Subscribe to the HHMI Bulletin

HHMI Bulletin: May 2012

Cover Story: Cells on the Move
Exploring the building blocks of cell movement, researchers are revealing delightful dances—and changing dogma.

Enter the Samurai
Loren Looger likes to solve other people's problems—at least their technical ones. That's working out well for his Janelia Farm colleagues.

Making Bigger Better
Scaling up research opportunities in introductory science courses requires a new way of thinking and working.

Opening the Floodgates
To speed the hunt for disease-related genes, researchers are delving into the exome, the fraction of the genome responsible for encoding proteins.